Differin 0.1% Cream / Gel (45g)


  • Treats mild to moderate acne
  • Active Ingredient: Adapalene
  • Easy to apply

Differin is a treatment gel for mild to moderate acne. The anti-inflammatory effect reduces soreness and irritation, helping to clear pores. A noticeable improvement in your skin may be seen within 1-4 weeks.

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Price (each) £33.80£35.16 £30.42£31.64 £27.04£28.13
SKU: DIFFERIN Categories: ,
1 x Cream£33.80In Stock
1 x Gel£35.16In Stock

Discreet Packaging

UK Based

  • Buy Differin Cream 0.1% Online

    My Pharmacy is the best place to Buy Differin Gel 0.1% in the UK. To Differin Cream In The UK you are required to have a prescription, which you can acquire with our free online consultation service.

    Buy Differin Gel 0.1% UK Next Day Delivery

    Through My Pharmacy You Can Buy Differin Cream 0.1% Online UK Next Day Delivery. Each treatment is sent out in secure and discreet packaging ensuring that you get your medicine on time and intact.

    Differin Gel UK

    Differin Gel UK is a retinoid treatment that contains the active ingredient Adapalene and is used to treat Acne. Differin Gel UK works by stopping the growth of cells and reduces both swelling and inflammation. Acne is a common skin condition that causes spots, oily and painful skin, mostly on the face, back or chest. You may be suffering from Acne and benefit from using Differin Gel UK if you suffer the following:
    • small red bumps containing white or yellow pus
    • Redness around the skin eruptions
    • Crusting of skin bumps
    • small red bumps
    • Redness around the spots
    • Scarring on the skin
    • Whiteheads
    • Blackheads
    See more information on Acne on the NHS website.

    Differin Cream 0.1%

    Differin Cream 0.1% is usually safe for the majority of people to use but there are a small number of people who should not use it. Do not use Differin Cream 0.1%:
    • If you are allergic to adapalene or any of the other ingredients of this medicine
    • Do not use Differin Cream 0.1% on areas where you have cuts or scrapes or on sunburnt skin or if you have a skin condition called eczema
    • Avoid contact with the eyes, mouth or other very sensitive areas of your body
    • Avoid exposure to strong sunlight and artificial UV light
    • If you experience sensitivity or irritation speak to your GP
    A Full list of warning and precautions are available to read in the patient information leaflet.

    Differin Adapalene

    Differin Adapalene can cause side effects but this does not mean everybody will get them. Some Differin Adapalene side effects include but are not limited to:
    • Dry skin
    • Irritation of the skin
    • Burning sensation of the skin
    • Redness of the skin
    • Local skin reaction
    • Skin discomfort
    • Sunburn
    • Itching of the skin
    • Peeling skin
    • Flare up of acne
    See a full list of Differin Adapalene side effects here.

    Differin Retinol

    No matter where you buy your Differin Retinol cream or which Differin Reviews that you read, you should always make sure you obtain it from a registered and trusted pharmacy. Any online pharmacy should be registered with the General Pharmaceutical Council and any online doctor service should registered with the Care Quality Commission and General Medical Council. If you are ever unsure you should contact the company for proof.

    Differin Acne Treatment

    Differin Acne Treatment directions are put in place to ensure it is safe for you to use and to minimise the risk of side effects. How to apply Differin Acne Treatment directions are:
    • Differin is only intended for use in adults and adolescents aged 12 years and over
    • This medicine is for EXTERNAL USE ONLY
    • Differin is applied at night before going to bed, unless your doctor has told you otherwise
    • Thoroughly wash the areas to be treated with water
    • Make sure the skin is clean and dry before using this medicine
    • Put a thin film of the cream with your fingertips on to the affected areas and rub in gently
    • Do not forget to wash your hands afterwards
    If you are ever unsure on how to use Differin Acne Treatment you should contact a pharmacist for advice.

    Differin Face Cream

    Differin Face Cream should be stored correctly to ensure safe use and to protect you, your family and the environment. You should store Differin Face Cream in the following way:
    • Keep this medicine out of the sight and reach of children
    • Do not use Differin Face Cream after the expiry date
    • Keep the medicine in its original container
    • Do not store above 25°C
    • Do not freeze
    • Return any unused Differin Anti Acne Gel to your local pharmacy for safe disposal

    Differin Anti Acne Gel

    Before using Differin Anti Acne Gel you should check to make sure you are not sensitive to any of its ingredients. Differin Anti Acne Gel active ingredient is
    • 1% w/w of Adapalene
    Differin Anti Acne Gel other ingredients are:
    • Carbomer 934P, macrogol-20 methyl glucose sesquistearate, glycerol (E422), natural squalane, methyl parahydroxybenzoate (E218), propyl parahydroxybenzoate (E216), disodium edetate, methyl glucose sesquistearate, phenoxyethanol, cyclomethicone, sodium hydroxide and purified water.

    Differin Before And After

    Differin Before And After research and reviews are frequently searching online by people who wish to use It in the near future. While searching Differin Before And After online you will come across many positive reviews from real people around the world one of these reviews states: “"I definitely feel better about myself. I feel more confident. Just the difference it’s made in my skin. Seeing my original photos—seeing the difference—it’s amazing in just 12 weeks. I wouldn’t want to stop using it” See more Differin Before And After reviews on the Differin Website.

    Differin Reviews

    At My Pharmacy we take great pride in providing all over customers with an outstanding service.  Through our free online prescription service, you can trust us to deliver a high-quality service with affordable medicine dispensed by our licensed UK Pharmacy. Many customers leave Differin Reviews via email or via the trust pilot section of the website so everyone can access them. One of our customer’s says “Differin Retinol Cream helped my Ance” You can view all our 5-Star Differin Reviews at Trustpilot Reviews.

    Do I Have To Use Differin Forever?

    You may wonder Do I Have To Use Differin Forever? Differin Cream treatment time varies from person to person and it also depends on the severity of your acne. How long you will have to Treatment depends on how fast your acne improves if you use it for 3 months you should see your GP for a review. If you require any further information on Do I Have To Use Differin Forever? Please contact us via the email address below.

    Can I Use Differin And Tretinoin Together?

    Can I Use Differin And Tretinoin Together? Is an important question to ask, so let’s have a look at the answer to Can I Use Differin And Tretinoin Together? You should not rely off any information searched online, you should not use Differin or tretinoin together unless your doctor has told you to. Using two creams together that have not been prescribed by a healthcare professional can cause reverse reactions and could even make your skin condition worse.

    Where Can I Buy Differin Gel?

    Where Can I Buy Differin Gel? Is commonly searched online and asked in many stores. Differin cream and Gel are prescription only medications so you would need a prescription from your GP to obtain it in store and if ordering online you would need to fill in a consultation to ensure it is safe for you to use. Please remember Differin Cream should only be ordered online if you have previously had it from your GP before. Here at My pharmacy we offer a wide range of Acne Treatments these include: If we can assist you with any questions like Where Can I Buy Differin Gel? Or if we can assist you with anything else please feel free to contact our helpful customer service team on info@mypharmacy.co.uk See a full list of our Acne treatments here at My Pharmacy.
  • Acne

    Acne is a common skin condition that affects most people at some point. It causes spots, oily skin and sometimes skin that’s hot or painful to touch.

    Acne most commonly develops on the:

    face – this affects almost everyone with acne
    back – this affects more than half of people with acne
    chest – this affects about 15% of people with acne
    Picture of acne spots
    Types of spots

    There are six main types of spot caused by acne:

    blackheads – small black or yellowish bumps that develop on the skin; they’re not filled with dirt, but are black because the inner lining of the hair follicle produces pigmentation (colouring)
    whiteheads – have a similar appearance to blackheads, but may be firmer and won’t empty when squeezed
    papules – small red bumps that may feel tender or sore
    pustules – similar to papules, but have a white tip in the centre, caused by a build-up of pus
    nodules – large hard lumps that build up beneath the surface of the skin and can be painful
    cysts – the most severe type of spot caused by acne; they’re large pus-filled lumps that look similar to boils and carry the greatest risk of causing permanent scarring
    What can I do if I have acne?
    These self-help techniques may be useful:

    Don’t wash affected areas of skin more than twice a day. Frequent washing can irritate the skin and make symptoms worse.
    Wash the affected area with a mild soap or cleanser and lukewarm water. Very hot or cold water can make acne worse.
    Don’t try to “clean out” blackheads or squeeze spots. This can make them worse and cause permanent scarring.
    Avoid using too much make-up and cosmetics. Use water-based products that are described as non-comedogenic (this means the product is less likely to block the pores in your skin).
    Completely remove make-up before going to bed.
    If dry skin is a problem, use a fragrance-free, water-based emollient.
    Regular exercise can’t improve your acne, but it can boost your mood and improve your self-esteem. Shower as soon as possible once you finish exercising, as sweat can irritate your acne.
    Wash your hair regularly and try to avoid letting your hair fall across your face.
    Although acne can’t be cured, it can be controlled with treatment. Several creams, lotions and gels for treating spots are available at pharmacies.

    If you develop acne, it’s a good idea to speak to your pharmacist for advice. Products containing a low concentration of benzoyl peroxide may be recommended – but be careful, as this can bleach clothing.

    If your acne is severe or appears on your chest and back, it may need to be treated with antibiotics or stronger creams that are only available on prescription.

    When to seek medical advice

    Treatments can take up to three months to work, so don’t expect results overnight. Once they do start to work, the results are usually good.

    Who’s affected?
    Acne is very common in teenagers and younger adults. About 80% of people aged 11 to 30 are affected by acne.

    Most people have acne on and off for several years before their symptoms start to improve as they get older. Acne often disappears when a person is in their mid-twenties.

    Your GP can diagnose acne by looking at your skin. This involves examining your face, chest and back for the different types of spot, such as blackheads or sore, red nodules.

    How many spots you have and how painful and inflamed they are will help determine how severe your acne is. This is important in planning your treatment.

    Four grades can be used to measure the severity of acne:

    grade 1 (mild) – acne is mostly confined to whiteheads and blackheads, with just a few papules and pustules
    grade 2 (moderate) – there are multiple papules and pustules, which are mostly confined to the face
    grade 3 (moderately severe) – there’s a large number of papules and pustules, as well as the occasional inflamed nodule, and the back and chest are also affected by acne
    grade 4 (severe) – there’s a large number of large, painful pustules and nodules
    Acne in women

    There’s a range of informally run message boards and blogs about acne on the web. You may find it supportive to read about other people’s experience of living with acne.

    For example, talkhealth provides a free acne support and information community.

    The Mix (formerly Get Connected) also has a website and helpline for teenagers and young people with emotional and other difficulties.

    Make-up can help cover up scars and can be particularly useful for facial scars.

    Camouflage make-up specially designed to cover up scars is available over the counter at pharmacies. You can also ask your GP for advice.

    If you’re interested in learning more about covering a mark, scar, non-infectious skin condition or a tattoo, you can also visit the Changing Faces skin camouflage service or call 0300 012 0276.

  • Side Effects

    Possible side effects

    Like all medicines, this medicine can cause side effects, although not everybody gets them.

    Differin Cream may cause the following side effects at the site of application.

    Common: may affect up to 1 in 10 people

    dry skin
    irritation of the skin
    burning sensation of the skin
    redness of the skin (erythema)
    Uncommon: may affect up to 1 in 100 people

    local skin reaction (contact dermatitis)
    skin discomfort
    itching of the skin (pruritus)
    peeling skin (exfoliation)
    flare up of acne
    Not known: frequency cannot be estimated from the available data

    allergic contact reaction
    pain or swelling of the skin
    irritation, redness, itching or swelling of the eyelids


  • Further Information

    Patient Information Leaflet