Epiduo Gel (45g)


  • Effective Antibiotic-Free Acne Cream
  • Active Ingredients: Adapalene And Benzoyl Peroxide
  • See Improvement Within 1-4 Weeks
  • Buy Online From UK Registered Pharmacy
  • Includes Free Prescription

Epiduo Gel is an effective treatment for acne. Epiduo acne cream contains two active ingredients to help treat spots: Adapalene which targets the skins acne-causing processes, and Benzoyl Peroxide which is an antimicrobial agent, softening and peeling the outer layer of skin. Apply Epiduo 2.5% Gel to clean skin once a day and you should see improvement to the affected area within 1 to 4 weeks.

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Product Description

Buy Epiduo Gel Online UK

My Pharmacy is the Best Place to Buy Epiduo 2.5 Gel in the UK in 2019. To buy Epiduo Cream online in the UK you are required to have a prescription, which you can acquire with our free online consultation service.

Epiduo Gel 30g in the UK with Next Day Delivery

Through My Pharmacy you can Buy Epiduo Gel UK Next Day Delivery. Each treatment is sent out in secure and discreet packaging ensuring that you get your medicine on time and intact.

What is Epiduo Gel?

We are often asked “What Epiduo Gel?”

Epiduo is used for the treatment of mild to moderate acne, for use by patients as young as nine-years-old. It contains two active ingredients called Adapalene and Benzoyl peroxide, both working together to help and reduce the acne you currently have and prevents any you may get in the future.

Having both of the above ingredients included reduces the amount of treatment you may need to keep re-purchasing. Using the specified amount on the affected areas, refills will only be need once every three months.

Currently Epiduo is only available via prescription and there is no existing generic version available, however, the two active ingredients (Adapalene & Benzoyl peroxide) can be bought separately over the counter and as prescription medications.

For more general information about Acne, click here to be directed to the NHS website.

Epiduo Gel Does it Work?

So the question is, Epiduo Gel does it work? Epiduo 2.5 gel works with the help of the active ingredients, Adapalene and Benzoyl peroxide. Both are acne-fighting ingredients, when combined, create one of the most effective methods of treating acne. It also helps tone down inflammation, particularly good news for people who tend to get red, inflamed pimples.

Firstly, Adapalene. Adapalene is a retinoid, acting specifically on the skin process that causes acne. It helps shed dead skin cells, keeping the pores from becoming blocked. This helps any future blemishes (mark, spot or discoloration) from reoccurring.

Benzoyl peroxide works differently. Benzoyl peroxide is something called an antimicrobial. These antimicrobials help fight the bacteria that cause acne outbreaks.

The amount of time it takes for Epiduo 2.5 gel to show any results usually takes eight to twelve weeks. If no improvement or signs of improvement have been procured, it is recommended to discontinue use and look for alternatives.

How Long Does it Take for Epiduo Gel to Work?

How long does it take for Epiduo Gel to work? Once treatment has been started, you may notice an initial flare up, this is common and can usually go worse before improving. The flare up can last up four weeks before improving.

This happens because the gel is making any current debris on the skin rise to the surface, this is usually not the case after eight weeks of continued appliance.

After the eight week mark, your skin should be showing signs of improvement, if this isn’t the case, consult with your doctor or dermatologist.

Adapalene Benzoyl Peroxide Epiduo 0.1 2.5 Gel

Epiduo 2.5 gel 30g contains two active ingredients called Adapalene and Benzoyl peroxide, both working together to help and reduce the acne you currently have and prevents any you may get in the future.

Firstly, Adapalene. Adapalene is a retinoid, acting specifically on the skin process that causes acne. It helps shed dead skin cells, keeping the pores from becoming blocked. This helps any future blemishes (mark, spot or discoloration) from reoccurring. Furthermore, Adapalene helps the efficiency and penetration of any other topical acne medication, thus it’s combined with Benzoyl.

Benzoyl peroxide works differently. Benzoyl peroxide is something called an antimicrobial. These antimicrobials help fight the bacteria that cause acne outbreaks. It’s listed on the world health organization’s list of essential medicines, making it one of the most effective and safe medications available.

Epiduo Gel How to Apply

This is a general use guide on Epiduo Gel How to Apply, if your doctor has guided you to use it differently, follow his/her instructions.

  • Applying the Epiduo gel is simple, modestly apply a pea-sized amount over clean and dry skin, once a day at bedtime.
  • Avoid the eyes, lips and nostrils.
  • After using Epiduo gel, wash your hands thoroughly.
  • Your doctor will tell you the length of treatment, this can vary.
  • If the effects of Epiduo are too strong or weak, talk to your doctor or pharmacist for guidance.

Epiduo Gel Review

Epiduo Gel Review by user Kimzzz

“Epiduo has changed my life. I am a 30 year old women always suffered from acne breakouts especially at that time of the month. My doctor prescribed me Epiduo three months ago to use once a night he advised me it wouldn’t work over night and to give it time. Within four weeks my skin completely cleared up and I haven’t had another spot since. The first week I suffered red dry skin so I used Sudocrem and persevered, my skin soon got used to it and now I use it every night as part of my routine. I hardly have any dark red marks left and I’ve never been happier. Give it a go and give it time.” –

(User Reviews for Epiduo, 2019)

Epiduo Gel review by the user TMarie12

“I have been suffering from adult acne for over a year and finally plucked up the courage to see the dermatologist for the first time in my life and boy, am I glad I did! I have been using Epiduo paired with an oral antibiotic (Solodyn) for about 1 1/2 months and my skin already looks better. I did have the redness on my first application (like a sunburn) and there was a good amount of dryness around my mouth for the first few weeks, but if you stop applying to those dry areas, it gets better. I also experienced some burning – but only in the dry areas. I didn’t really have an initial breakout, just a few little pimples that were NOTHING like the huge cysts that I had been so used to getting. Another pro – my skin is SO SOFT now.” –

(User Reviews for Epiduo, 2019)

Buy Epiduo Gel UK next day delivery from My Pharmacy UK.

Duac Gel or Epiduo Gel

Here are some of the differences between Duac Gel and Epiduo Gel –

One of the first differences a lot of people notice is the significant increase in dryness when using Epiduo compared to Duac, with the former causing higher volumes of evaporative water loss on the skin.

Users testing the difference between the two also noted a higher frequency of adverse perceptions, including mild burning and stinging when using Epiduo Gel compared to Duac Gel.

Overall the two of them barely have any significant differences between them when comparing common side effects.

Another difference is that both use changed active ingredients. Epiduo gel contains Adapalene and Benzoyl peroxide, whilst Duac Gel contains Clindamycin and Benzoyl peroxide. Clindomycin works by slowing or stopping the growth of bacteria, treating certain types of bacterial infections, including the skin.

Duac Gel is available to be purchased from My Pharmacy UK, click here for a range of pricing options.

Epiduo Acne Gel Side Effects

Like with all medicine, Epiduo 2.5 gel can have side effects, but these aren’t experienced by everyone.

Stop using this product and seek immediate medical attention if you develop throat tightness or swelling of the eyes, face, lips or tongue, feel faint, or have difficulty breathing. The frequency at which these side effects occur is not known. This could mean you have an adverse allergic reaction to the medicine.

Some of the common side effects include –

  • Scaling
  • Redness
  • Skin irritation
  • Burning sensation
  • Dry skin
  • Skin rash

Uncommon side effects include –

  • Itchy skin
  • Sunburn

For more information on the side effects of Epiduo Gel, please consult the patient information leaflet located here.

Alternatives to Epiduo Gel 30g

My Pharmacy UK is the best place to Buy Epiduo Gel UK.

If Epiduo isn’t viable for you, here are some alternatives to Epiduo Gel 30g –


Acne is a common skin condition that affects most people at some point. It causes spots, oily skin and sometimes skin that’s hot or painful to touch.

Acne most commonly develops on the:

face – this affects almost everyone with acne
back – this affects more than half of people with acne
chest – this affects about 15% of people with acne
Picture of acne spots
Types of spots

There are six main types of spot caused by acne:

blackheads – small black or yellowish bumps that develop on the skin; they’re not filled with dirt, but are black because the inner lining of the hair follicle produces pigmentation (colouring)
whiteheads – have a similar appearance to blackheads, but may be firmer and won’t empty when squeezed
papules – small red bumps that may feel tender or sore
pustules – similar to papules, but have a white tip in the centre, caused by a build-up of pus
nodules – large hard lumps that build up beneath the surface of the skin and can be painful
cysts – the most severe type of spot caused by acne; they’re large pus-filled lumps that look similar to boils and carry the greatest risk of causing permanent scarring
What can I do if I have acne?
These self-help techniques may be useful:

Don’t wash affected areas of skin more than twice a day. Frequent washing can irritate the skin and make symptoms worse.
Wash the affected area with a mild soap or cleanser and lukewarm water. Very hot or cold water can make acne worse.
Don’t try to “clean out” blackheads or squeeze spots. This can make them worse and cause permanent scarring.
Avoid using too much make-up and cosmetics. Use water-based products that are described as non-comedogenic (this means the product is less likely to block the pores in your skin).
Completely remove make-up before going to bed.
If dry skin is a problem, use a fragrance-free, water-based emollient.
Regular exercise can’t improve your acne, but it can boost your mood and improve your self-esteem. Shower as soon as possible once you finish exercising, as sweat can irritate your acne.
Wash your hair regularly and try to avoid letting your hair fall across your face.
Although acne can’t be cured, it can be controlled with treatment. Several creams, lotions and gels for treating spots are available at pharmacies.

If you develop acne, it’s a good idea to speak to your pharmacist for advice. Products containing a low concentration of benzoyl peroxide may be recommended – but be careful, as this can bleach clothing.

If your acne is severe or appears on your chest and back, it may need to be treated with antibiotics or stronger creams that are only available on prescription.

When to seek medical advice

Treatments can take up to three months to work, so don’t expect results overnight. Once they do start to work, the results are usually good.

Who’s affected?
Acne is very common in teenagers and younger adults. About 80% of people aged 11 to 30 are affected by acne.

Most people have acne on and off for several years before their symptoms start to improve as they get older. Acne often disappears when a person is in their mid-twenties.

Your GP can diagnose acne by looking at your skin. This involves examining your face, chest and back for the different types of spot, such as blackheads or sore, red nodules.

How many spots you have and how painful and inflamed they are will help determine how severe your acne is. This is important in planning your treatment.

Four grades can be used to measure the severity of acne:

grade 1 (mild) – acne is mostly confined to whiteheads and blackheads, with just a few papules and pustules
grade 2 (moderate) – there are multiple papules and pustules, which are mostly confined to the face
grade 3 (moderately severe) – there’s a large number of papules and pustules, as well as the occasional inflamed nodule, and the back and chest are also affected by acne
grade 4 (severe) – there’s a large number of large, painful pustules and nodules
Acne in women

There’s a range of informally run message boards and blogs about acne on the web. You may find it supportive to read about other people’s experience of living with acne.

For example, talkhealth provides a free acne support and information community.

The Mix (formerly Get Connected) also has a website and helpline for teenagers and young people with emotional and other difficulties.

Make-up can help cover up scars and can be particularly useful for facial scars.

Camouflage make-up specially designed to cover up scars is available over the counter at pharmacies. You can also ask your GP for advice.

If you’re interested in learning more about covering a mark, scar, non-infectious skin condition or a tattoo, you can also visit the Changing Faces skin camouflage service or call 0300 012 0276.

Further Information

Further information can be found on the manufacturers
Paitient Information Leaflet and printed if required.

Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Epiduo may cause the following side effects at the site of application.

Common side effects (may affect up to 1 in 10 people)

dry skin
local skin rash (irritative contact dermatitis)
burning sensation
irritation of the skin
Uncommon side effects (may affect up to 1 in 100 people)

itching of the skin (pruritus)
Not known (frequency cannot be estimated from the available data): swelling face, allergic contact reactions, swelling of the eyelid, tightness in the throat, pain of skin (stinging pain), blisters (vesicles).

If skin irritation appears after application of Epiduo, it is generally mild to moderate, with local signs as redness, dryness, scaling, burning and pain of skin (stinging pain), which peak during the first week and resolve without additional treatment.

Do not use Epiduo:

if you are allergic to the active substances or any of the other ingredients of this medicine (listed in section 6).
Warnings and precautions

You should not use Epiduo on areas where you have cuts, scrapes or eczema.
Make sure Epiduo does not get into your eyes, mouth or nostrils, and other very sensitive areas of the body. Should this occur wash these areas immediately with plenty of warm water.
Avoid excessive exposure to sunlight and UV lamps.
Avoid getting Epiduo on your hair or coloured fabrics as it may bleach them and wash your hands thoroughly after you have used the medicine.