Epiduo Gel 2.5% – Acne Cream (45g)


Epiduo Gel is an effective treatment for acne. Epiduo acne cream contains two active ingredients to help treat spots: Adapalene which targets the skins acne-causing processes, and Benzoyl Peroxide which is an antimicrobial agent, softening and peeling the outer layer of skin. Apply Epiduo 2.5% Gel to clean skin once a day and you should see improvement to the affected area within 1 to 4 weeks.

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Product Description

Epiduo Gel 2.5% is an effective treatment for acne. Epiduo acne cream contains two active ingredients to help treat spots: Adapalene which targets the skins acne-causing processes, and Benzoyl Peroxide which is an antimicrobial agent, softening and peeling the outer layer of skin. Apply Epiduo 2.5% Gel to clean skin once a day and you should see improvement to the affected area within 1 to 4 weeks.

For more information about Acne, click here.


Do you suffer from Acne? Epiduo gel is an effective treatment.

This gel combines two active ingredients, Adapalene and Benzoyl peroxide which work together but in different ways:

Adapalene belongs to a group of products known as retinoids and acts specifically on the skin processes that cause acne.

The other active ingredient is benzoyl peroxide, This works as an antimicrobial agent and by softening and peeling the outer layer of the skin.

How To Apply Epiduo gel

You should Apply a thin film of gel evenly over acne affected areas once a day at bedtime. Avoid the eyes, lips and nostrils. Clean the skin and dry it before application. Wash your hands thoroughly after you have used Epiduo gel.

Epiduo starts working immediately and results can be seen after 1 to 4 weeks of treatment.

Continue treatment, acne will improve over time.



Acne is a common skin condition that affects most people at some point. It causes spots, oily skin and sometimes skin that’s hot or painful to touch.

Acne most commonly develops on the:

face – this affects almost everyone with acne
back – this affects more than half of people with acne
chest – this affects about 15% of people with acne
Picture of acne spots
Types of spots

There are six main types of spot caused by acne:

blackheads – small black or yellowish bumps that develop on the skin; they’re not filled with dirt, but are black because the inner lining of the hair follicle produces pigmentation (colouring)
whiteheads – have a similar appearance to blackheads, but may be firmer and won’t empty when squeezed
papules – small red bumps that may feel tender or sore
pustules – similar to papules, but have a white tip in the centre, caused by a build-up of pus
nodules – large hard lumps that build up beneath the surface of the skin and can be painful
cysts – the most severe type of spot caused by acne; they’re large pus-filled lumps that look similar to boils and carry the greatest risk of causing permanent scarring
What can I do if I have acne?
These self-help techniques may be useful:

Don’t wash affected areas of skin more than twice a day. Frequent washing can irritate the skin and make symptoms worse.
Wash the affected area with a mild soap or cleanser and lukewarm water. Very hot or cold water can make acne worse.
Don’t try to “clean out” blackheads or squeeze spots. This can make them worse and cause permanent scarring.
Avoid using too much make-up and cosmetics. Use water-based products that are described as non-comedogenic (this means the product is less likely to block the pores in your skin).
Completely remove make-up before going to bed.
If dry skin is a problem, use a fragrance-free, water-based emollient.
Regular exercise can’t improve your acne, but it can boost your mood and improve your self-esteem. Shower as soon as possible once you finish exercising, as sweat can irritate your acne.
Wash your hair regularly and try to avoid letting your hair fall across your face.
Although acne can’t be cured, it can be controlled with treatment. Several creams, lotions and gels for treating spots are available at pharmacies.

If you develop acne, it’s a good idea to speak to your pharmacist for advice. Products containing a low concentration of benzoyl peroxide may be recommended – but be careful, as this can bleach clothing.

If your acne is severe or appears on your chest and back, it may need to be treated with antibiotics or stronger creams that are only available on prescription.

When to seek medical advice

Treatments can take up to three months to work, so don’t expect results overnight. Once they do start to work, the results are usually good.

Who’s affected?
Acne is very common in teenagers and younger adults. About 80% of people aged 11 to 30 are affected by acne.

Most people have acne on and off for several years before their symptoms start to improve as they get older. Acne often disappears when a person is in their mid-twenties.

Your GP can diagnose acne by looking at your skin. This involves examining your face, chest and back for the different types of spot, such as blackheads or sore, red nodules.

How many spots you have and how painful and inflamed they are will help determine how severe your acne is. This is important in planning your treatment.

Four grades can be used to measure the severity of acne:

grade 1 (mild) – acne is mostly confined to whiteheads and blackheads, with just a few papules and pustules
grade 2 (moderate) – there are multiple papules and pustules, which are mostly confined to the face
grade 3 (moderately severe) – there’s a large number of papules and pustules, as well as the occasional inflamed nodule, and the back and chest are also affected by acne
grade 4 (severe) – there’s a large number of large, painful pustules and nodules
Acne in women

There’s a range of informally run message boards and blogs about acne on the web. You may find it supportive to read about other people’s experience of living with acne.

For example, talkhealth provides a free acne support and information community.

The Mix (formerly Get Connected) also has a website and helpline for teenagers and young people with emotional and other difficulties.

Make-up can help cover up scars and can be particularly useful for facial scars.

Camouflage make-up specially designed to cover up scars is available over the counter at pharmacies. You can also ask your GP for advice.

If you’re interested in learning more about covering a mark, scar, non-infectious skin condition or a tattoo, you can also visit the Changing Faces skin camouflage service or call 0300 012 0276.

Further information can be found on the manufacturers
Paitient Information Leaflet and printed if required.

Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Epiduo may cause the following side effects at the site of application.

Common side effects (may affect up to 1 in 10 people)

dry skin
local skin rash (irritative contact dermatitis)
burning sensation
irritation of the skin
Uncommon side effects (may affect up to 1 in 100 people)

itching of the skin (pruritus)
Not known (frequency cannot be estimated from the available data): swelling face, allergic contact reactions, swelling of the eyelid, tightness in the throat, pain of skin (stinging pain), blisters (vesicles).

If skin irritation appears after application of Epiduo, it is generally mild to moderate, with local signs as redness, dryness, scaling, burning and pain of skin (stinging pain), which peak during the first week and resolve without additional treatment.

Do not use Epiduo:

if you are allergic to the active substances or any of the other ingredients of this medicine (listed in section 6).
Warnings and precautions

You should not use Epiduo on areas where you have cuts, scrapes or eczema.
Make sure Epiduo does not get into your eyes, mouth or nostrils, and other very sensitive areas of the body. Should this occur wash these areas immediately with plenty of warm water.
Avoid excessive exposure to sunlight and UV lamps.
Avoid getting Epiduo on your hair or coloured fabrics as it may bleach them and wash your hands thoroughly after you have used the medicine.