Mefenamic Acid 500mg Tablets


  • Effective Period Pain Treatment
  • Active Ingredient: Mefenamic Acid
  • Relieves Moderately Severe Pain
  • Buy With Confidence From UK Registered Pharmacy
  • Includes Free Prescription

Period pain is experienced by most women at some point in their lives as a normal part of their menstrual cycle. The pain can be felt in the tummy and sometimes the back and thighs. The pain can feel like either intense spasms (cramps) or a constant dull ache. Mefenamic Acid is a non-steroidal anti-inflammatory drug that tackles period pain head-on shortly after being taken, easing your discomfort to get on with your day. It can also be used to relieve moderately severe pain, such as muscular aches and pains, headaches, and dental pain.

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    1. Introduction
    2. What is Mefenamic Acid?
    3. What Causes Period Pain?
    4. Mefenamic Acid for Period Pain
    5. How to Use Mefenamic Acid Effectively
    6. Ordering Mefenamic Acid from My Pharmacy
    7. Other Options for Period Pain Relief
    8. Mefenamic Acid: Dosages and Forms
    9. Potential Side Effects
    10. Interactions with Other Medications
    11. Frequently Asked Questions
    12. Conclusion


    Welcome to My Pharmacy, your trusted online pharmacy based in the UK. We offer a wide range of prescription treatments with the convenience of next-day delivery to your doorstep. For those who experience period pain, we offer Mefenamic Acid, a prescription medication that can provide effective relief. To get started, use our free online consultation service to obtain your prescription.  

    What is Mefenamic Acid?

    Mefenamic Acid is a prescription medication classified as a nonsteroidal anti-inflammatory drug (NSAID). Available in both branded (Ponstel) and generic forms, it works by inhibiting cyclo-oxygenase enzymes, thereby reducing the production of prostaglandins—chemicals associated with pain and inflammation. For a more comprehensive understanding of this drug, consult the patient information leaflet or speak with a healthcare professional.  

    What Causes Period Pain?

    Period pain, medically known as dysmenorrhea, can be caused by a variety of factors including:
    1. Contraction of the Uterus: The primary cause of period cramps.
    2. Endometriosis: A condition where tissue similar to the uterine lining grows outside the uterus.
    3. Uterine Fibroids: Non-cancerous growths in the uterus.
    To know more, read this in-depth article from the NHS or watch this informative Youtube video: ‘What causes period pain?’.  

    Mefenamic Acid for Period Pain

    Many women experience period pain at various stages of their lives. The severity and frequency can differ from one individual to another. Mefenamic Acid effectively reduces pain and lessens menstrual blood flow. Unlike over-the-counter pain relievers like paracetamol, it has proven to be more effective in providing relief. For further details, you may refer to this scientific study outlining the efficacy of NSAIDs for period pain.  

    How to Use Mefenamic Acid Effectively

    Proper usage of Mefenamic Acid can make a significant difference in its effectiveness. For the best results, follow these steps:
    1. Take the capsule with a full glass of water.
    2. It's usually advised to take the medication with food to avoid stomach-related side effects.
    3. Follow the exact dosage given by your healthcare provider.
    4. Don't lie down for at least 10 minutes after taking Mefenamic Acid.

    Ordering Mefenamic Acid from My Pharmacy

    My Pharmacy offers Mefenamic Acid in both 250mg and 500mg tablets, available in multiple pack sizes. To place an order:
    1. Complete our online consultation
    2. Obtain your prescription
    3. Choose your preferred dosage and pack size
    4. Enjoy discreet, next-day delivery
    For further assistance, watch our YouTube tutorial on how to place an order.

    Other Options for Period Pain Relief

    Apart from Mefenamic Acid, various treatments are available:
    • Over-the-counter medications like ibuprofen or aspirin
    • Lifestyle modifications such as exercise and heat therapy
    • Alternative treatments like acupuncture and herbal remedies
    While Mefenamic Acid is effective, there are other options such as Ponstan, Tranexamic Acid and Naproxen. Combined Contraceptive Pills can also help with heavy periods. Explore our range of period pain relief options for more information.

    Mefenamic Acid: Dosages and Forms

    Before starting treatment, consult your healthcare provider for personalized dosage recommendations. Typically, Mefenamic Acid is available in 250mg capsules and 500mg tablets, which can be taken three times a day. To minimize potential stomach side effects, it's advisable to take the medication with food.

    Potential Side Effects

    While most individuals do not experience significant side effects, potential issues can include:
    • Nausea
    • Stomach pain
    • Dizziness
    If you encounter severe symptoms, seek immediate medical attention. Consult your healthcare provider or read the patient information leaflet for complete details.  

    Interactions with Other Medications

    Avoid combining Mefenamic Acid with other NSAIDs or paracetamol, as this could increase the risk of adverse side effects. If you are currently on other medications, consult your healthcare provider for guidance.  

    Frequently Asked Questions

    • Can I take Mefenamic Acid for an extended period?
    Always follow your healthcare provider's recommendations for the duration of treatment.
    • Is Mefenamic Acid available through the NHS?
    Yes, you can order repeat NHS prescriptions from My Pharmacy with next-day delivery.
    • Is it safe to drink alcohol while taking Mefenamic Acid?
    Alcohol increases the risk of stomach bleeding. Avoid alcohol consumption while taking this medication.
    • How soon will I feel relief after taking Mefenamic Acid?
    Effects vary, but many users report feeling relief within 30 minutes to an hour.  


    Managing period pain can be an overwhelming experience, given the multitude of options available. This is why medications like Mefenamic Acid are pivotal in providing targeted relief. They offer a specialised treatment that focuses on reducing the pain and inflammation associated with menstrual cramps, thereby enhancing your quality of life. By inhibiting the production of chemicals like prostaglandins, which trigger inflammation and pain, Mefenamic Acid serves as an effective tool in your period pain management kit. But remember, Mefenamic Acid is a prescription-only medication, which means it’s essential to consult a healthcare provider for accurate diagnosis and treatment plans. At My Pharmacy, we offer a convenient online consultation service, ensuring you can quickly access effective treatments like Mefenamic Acid 250mg capsules or Mefenamic Acid 500mg tablets without a hassle. And while medications play an integral role in managing your symptoms, they are often most effective when combined with lifestyle changes. So, don't overlook the importance of proper diet, exercise, and even natural remedies. They can be particularly beneficial for those looking for a holistic approach to managing period pain and may help reduce your dependence on medications over time. So, whether you're new to experiencing period pain or have been battling it for years, My Pharmacy is here to help you navigate your options. From providing detailed medication information to offering next-day delivery services, we aim to make your health journey as smooth as possible.  
  • Period Pain

    Period pain is common and a normal part of your menstrual cycle. Most women experience it at some point in their lives.

    It’s usually felt as painful muscle cramps in the tummy, which can spread to the back and thighs.

    The pain sometimes comes in intense spasms, while at other times it may be dull but more constant.

    What causes period pain?
    Period pain occurs when the muscular wall of the womb tightens (contracts).
    During your period, the wall of the womb starts to contract more vigorously to encourage the womb lining to shed away as part of your monthly period.

    When the muscular wall of the womb contracts, it compresses the blood vessels lining your womb. This temporarily cuts off the blood supply – and hence oxygen supply – to your womb. Without oxygen, the tissues in your womb release chemicals that trigger pain.

    While your body is releasing these pain-triggering chemicals, it’s also producing other chemicals called prostaglandins. These encourage the womb muscles to contract more, further increasing the level of pain.

    Period pain caused by a condition
    Less commonly, period pain can be caused by an underlying medical condition. Doctors sometimes call this secondary dysmenorrhoea.

    Period pain linked to an underlying condition tends to affect older women. Women aged 30 to 45 are most commonly affected.

    Conditions that can cause period pain include:

    endometriosis – where cells that normally line the womb start to grow in other places, such as in the fallopian tubes and ovaries; these cells can cause intense pain when they shed and fall away
    fibroids – non-cancerous tumours that can grow in the womb and can make your periods heavy and painful
    pelvic inflammatory disease – where your womb, fallopian tubes and ovaries become infected with bacteria, causing them to become severely inflamed
    adenomyosis – where the tissue that normally lines the womb starts to grow within the muscular womb wall, making your periods particularly painful

  • Side Effects

    Like all medicines Mefenamic Acid can cause side effects, although not everybody gets them.
    All medicines can cause allergic reactions although serious

    allergic reactions are rare. Any sudden wheeziness, difficulty in breathing, swelling of the eyelids, face or lips, rash or itching
    (especially affecting your whole body) should be reported to a
    doctor immediately.

    Do not take if you have a peptic ulcer (ulcer in your stomach, or intestines) or bleeding in your stomach, or have had two or more
    episodes of peptic ulcer, stomach bleeding or perforation.
    STOP TAKING the medicine and tell your doctor if you experience:
    • Indigestion or heart burn • Abdominal Pain (pains in your stomach) or other abdominal
    (stomach) symptoms. If you suffer from any of the following at anytime during your treatment
    STOP TAKING the medicine and see a doctor immediately.
    • Pass blood in your stools/motions • Pass loose stool (Diarrhoea) • Pass black tarry stools • Vomit any blood or dark particles that look like coffee grounds.

    Other Side Effects:
    • Mouth ulcers, malaise, fatigue, unexplained bruising, fever or sore throat may occasionally occur, if you notice any of these symptoms speak to your doctor as they may be signs of a blood disorder • If a skin rash or jaundice (yellowing of the skin or whites of eyes) occur, tell your doctor • Nausea (feeling sick), vomiting (being sick), loss of appetite • Fits • Rapid heart beats • Reactions to the sun • You may notice urinary symptoms such as blood in the urine or an increase or decrease in the amount of urine, ankle swelling, reduced salt levels in the body • Symptoms such as sleep disturbance, depression, confusion, nervousness, hallucinations (imagining sensations), noise in the ears or impaired hearing, vertigo, dizziness, tingling or other odd sensations, problems with your eyesight or drowsiness have occasionally been reported • Symptoms of aseptic meningitis such as, over-reaction of the skin to sunlight, persistent headache, a stiff neck, fever, drowsiness or muscle pain may occur in some patients (especially in patients with existing auto immune disorders, such as systemic lupus erythematosus, mixed connective tissue disease) • Medicines such as mefenamic acid may be associated with a small
    increased risk of heart attack (“myocardial infarction”) or stroke. Any risk is more likely with high doses and prolonged treatment. Do not exceed the recommended dose or duration of treatment. If you have heart problems, previous stroke or think that you might be at risk of
    these conditions (for example if you have high blood pressure, diabetes or high cholesterol or are a smoker) you should discuss your treatment with your doctor or pharmacist

  • Further Information

    Patient Information Leaflet