Wegovy Tablets

Wegovy Tablets

• – May be available in UK late 2026 based on manufacturer’s press release, though this is only an estimate and does not reflect a real timeline.
• – Once daily tablet for weight loss that has been shown to help lose an average of 14% body weight over 68 weeks in clinical trials.
• – Wegovy tablets are not currently licensed in the UK. Providers offering this item are not regulated and should be considered unsafe. This page is for information purposes only.

About Wegovy tablets

Wegovy tablets are an oral version of the Wegovy weight loss injection. While both contain the active ingredient semaglutide, instead of injecting yourself with the medication once a week, you swallow a daily tablet. 

How do Wegovy tablets work?

Wegovy tablets contain the same active ingredient as Wegovy injections: semaglutide. This means that they work in the same way.

Semaglutide is a medicine known as a GLP-1 receptor agonist. This means it takes on the role of GLP-1 in your body, a natural hormone responsible for managing your blood sugar and regulating your appetite.

By mimicking this hormone, the Wegovy tablets work by:

• – reducing appetite and food cravings (food noise)
• – helping you feel fuller for longer after meals
• – regulating blood sugar, preventing spikes and food cravings

Wegovy vs Rybelsus explained

Both Wegovy tablets and Rybelsus contain semaglutide, meaning they work as GLP-receptor agonists. However, they’re approved to treat different conditions, and have different maximum doses:

• – Wegovy: approved to treat type 2 diabetes and weight loss in injection form (Wegovy tablets have not yet been approved for use in the UK). Comes in 1.5mg, 4mg, 9mg and 25mg doses.
• – Rybelsus: approved to treat type 2 diabetes. Comes in 1.5mg, 5mg and 9mg.

What’s the difference between Wegovy tablets and injections?

Here are the biggest differences between Wegovy tablets and injections:

• – Doses: Both the tablets and injections start at a lower dose and increase over time. However, the actual doses are different as your body takes in the medicine in different ways. For injections the medicine is absorbed into the bloodstream, while tablets are taken in through the digestive system.
• – Efficacy: On average, people taking the tablets lose around 14% of their body weight, compared to around 21% with the injections.
• – Frequency: You take the tablet once a day in the morning. The injection is taken once a week.

Wegovy tablets are not yet approved in the UK, but they are expected to become available later this year.

Wegovy tablets: clinical trial results

Wegovy tablets have been shown to be effective in helping lose weight, compared to a placebo.

The OASIS 4 trial, carried out in late 2025, looked at the use of oral semaglutide (Wegovy tablets) in adults who were overweight or obese over 71 weeks. Importantly the tablets were only studied over the course of 68 weeks.

The average weight lost among participants who were taking Wegovy tablets was 14% of their total body weight.

Over 1 in 4 people (28%) taking Wegovy tablets lost over 20% of their body weight over 68 weeks, showing similar numbers to 7.2mg Wegovy injections, which had an average weight loss of 21% over 72 weeks.

Wegovy tablets dosage

The current Wegovy tablet doses available in the US are:

• – 1.5mg
• – 4mg
• – 9mg
• – 25mg

Importantly, as the tablet is absorbed into the body in a different way, the doses are not the same as Wegovy injections.

Wegovy tablets eligibility

As Wegovy tablets are not yet available in the UK, we do not currently know who will be eligible to use them if they get approved.

Wegovy tablets availability

In the UK, Wegovy tablets could be available for weight loss in the UK later in 2026.

They are currently under review and will need to be approved by the Medicine and Healthcare Regulatory Agency (MHRA), as well as the National Institute for Health and Care Excellence (NICE).

If the tablets are approved for use in the UK, it will be available through legitimate and regulated online services, like myPharmacy.

Wegovy tablets became widely available in the USA early in 2026, after being approved by the U.S. Food and Drug Administration (FDA) a few months earlier.

Wegovy tablets cost

It’s not currently known how much Wegovy tablets will cost in UK. The cost will depend on a few factors, like:

• – the price the manufacturer (Novo Nordisk) sets for the UK market
• – availability of Wegovy pills in the UK
• – what strength/dose someone is taking

Weight loss from clinical studies across treatments

	Wegovy Tablets	Wegovy Injections	Mounjaro Injections	Xenical	Mysimba
Active Ingredient	Semaglutide	Semaglutide	Tirzepatide	Orlistat	Naltrexone & Bupropion
Manufacturer	Novo Nordisk	Novo Nordisk	Eli Lilly	Roche	Orexigen
Weight loss during clinical studies	14%	21%	22.5%	5–10%	5–8%

Directions of use

The directions for Wegovy tablets (as they’ve been approved in the US) are as follows:

• – Take one tablet a day. Take first thing in the morning, on an empty stomach, with a small sip of water.
• – Tablets are swallowed whole. They cannot be split or crushed.
• – Wegovy tablets should be taken at least 30 minutes before you eat, drink, or take any other medication.

Potential side effects of Wegovy tablets – as reported in US studies

Like any medication, Wegovy can cause side effects in some, though they are usually mild and manageable. Side effects are most likely to happen when you first start treatment but will usually go away on their own as your body gets used to the medication.

Common side effects include:

• – nausea or vomiting
• – diarrhoea
• – constipation
• – sulphur burps

Warnings

You should or avoid this medication if:

• – you are under 18, pregnant or breastfeeding
• – have a personal or family history of certain types of thyroid cancer
• – are allergic to semaglutide
• – have multiple endocrine neoplasia syndrome 2

Frequently asked questions about Wegovy tablets

Are Wegovy tablets cheaper than weight loss injections?

Currently, we do not know what the price of Wegovy tablets will be in the UK, even compared to weight loss injections, as it has not yet been approved by the MHRA.

Will Wegovy tablets be available on the NHS?

If approved in the UK, it’s likely that Wegovy tablets will eventually be available on the NHS. This is because Wegovy injections are already available on the NHS.

Sources

• – Wegovy® Safety and Side Effects. Novo Nordisk. [Accessed on 7 April 2026].
• – Weight Management Injections (Including Semaglutide). NHS England. [Accessed on 7 April 2026].
• – How to Start Wegovy®. Novo Nordisk. [Accessed on 7 April 2026].
• – What to Pay for Wegovy®. Novo Nordisk. [Accessed on 7 April 2026].
• – Obesity Management and Pharmacotherapy (2025). BMJ. [Accessed on 7 April 2026].
• – Effect of Semaglutide on Weight Management (2025). New England Journal of Medicine. [Accessed on 7 April 2026].
• – Semaglutide Tablets (Rybelsus®): Changes in Formulation, Dosing and Tablet Size (2025). NHS Tayside Area Drug and Therapeutics Committee. [Accessed on 7 April 2026].
• – EMA Concludes Review of Weight-Management Medicine Mysimba. European Medicines Agency. [Accessed on 7 April 2026].
• – Pharmacological Treatment of Obesity: A Review (2011). International Journal of Obesity. [Accessed on 7 April 2026].
• – Once-Weekly Tirzepatide in Adults with Overweight or Obesity (2022). New England Journal of Medicine. [Accessed on 7 April 2026].
• – Semaglutide and Long-Term Weight Outcomes (2025). PubMed. [Accessed on 7 April 2026].