Tibolone (Generic Livial) (28 Tablets)


  • Generic product image for illustration
  • Non-hormonal ingredients
  • effective relief from menopause symptoms
  • Buy With Confidence From UK Registered Pharmacy
  • Includes Free Prescription

Livial 2.5 mg tablets provide relief from menopausal symptoms, including osteoporosis. It is a form of hormone replacement therapy (HRT).

Livial contains one ingredient, Tibolone, which breaks down in the body into components which emulate the sex hormones oestrogen, progesterone and testosterone.

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What is Tibolone  and what it is used for?

Tibolone 2.5 mg tablets are the generic equivalent to Livial and is a Hormone Replacement Therapy (HRT).
Tibolone, a substance that has favorable effects on different tissues in the body, such as brain, vagina and bone.
This medicine is used in postmenopausal women with at least 12 months (1 year) since their last natural period.

This medicine is used for:
Relief of symptoms occurring after menopause
During the menopause, the amount of the oestrogen produced by a woman’s body drops. This can
cause symptoms such as hot face, neck and chest (“hot flushes”). Tibolone alleviates these symptoms
after menopause. You will only be prescribed this medicine if your symptoms seriously hinder
your daily life.

Prevention of osteoporosis
After the menopause some women may develop fragile bones (osteoporosis). You should discuss
all available options with your doctor.
If you are at an increased risk of fractures due to osteoporosis and other medicines are not
suitable for you, you can use  Tiboloneto prevent osteoporosis after menopause.

There are three different kinds of HRT:
• Oestrogen-only HRT
• Combined HRT, containing two kinds of female hormone, an oestrogen and a progestogen.
• Livial, which contains a substance called tibolone
Tiboloneis different from other HRT. Instead of actual hormones (such as oestrogen and
progestogen) it contains tibolone. Your body breaks down tibolone to make hormones. Its effects
and benefits are similar to combined HRT.

How does Tibolone work?

The menopause is a natural part of ageing that usually occurs between 45 and 55 years of age.
The levels of oestrogen and progesterone produced by the female body decrease and fluctuate as a woman ages.
This change in hormone levels cause the menopause and its symptoms the symptoms such as hot flushes and mood swings. Generally these symptoms are mild and HRT is only prescribed if the symptoms seriously hinder your daily life.

Tibolone is different to other kinds of HRT. Instead of containing only oestrogen or a combination of oestrogen and progestogen, it contains an ingredient called Tibolone.
Tibolone is broken down in the body into an oestrogen and a progestogen, tibolone works in a similar way to combined HRT.

You will have no monthly bleed when taking Tibolone tablets but you may have some irregular bleeding or spotting during the first 6 months of taking this medication. If it continues after 6 months, you should speak to your doctor.

How do you take Livial?

The recommended dose is one tablet every day.
Press the tablet so that it comes through the foil. Swallow the tablet with some water or other drink, without chewing. Take Tibolone at the same time each day.
The strips of tablets are marked with the days of the week. Start by taking a tablet marked with
the current day. Start the next strip the next day. Do not leave a break between strips or packs

If you forget to take your tablet at the usual time, take it as soon as you remember unless you are 12 hours late. If you are more than 12 hours late taking a tablet, skip it and take your next tablet at the correct time. You should never take a double dose to make up for a forgotten tablet.

When you start takingTibolone  for the first time, you should follow these guidelines:

  • If you have had a natural period in the last 12 months, you shouldn’t take Tibolone . It should be at least 12 months since your last natural period.
  • You can start taking Tibolone straight away if you’ve never used HRT before, if you’re changing from a form of HRT that doesn’t give you a monthly bleed, if you’ve been prescribed HRT because you had a hysterectomy, or if you are being treated for endometriosis.
  • If you are taking a kind of HRT that gives you a monthly bleed, you should wait until the end of your next period before starting Livial.

How effective is Tibolone ?

Tibolone tablets are clinically proven to help ease menopause symptoms as long as they are taken as prescribed by your doctor.

With any HRT treatment, your doctor will want to make sure you are on the lowest dose possible for the shortest amount of time to control your symptoms. For this reason it’s important you see your GP at least annually so they can monitor your symptoms accurately.

You should also make sure you have your breasts screened regularly, as well as carrying out regular checks yourself. You should also make sure that your cervical smear tests are up to date.

There are certain lifestyle changes you can make to help your medication work efficiently. These include exercising regularly, giving up smoking, eating as healthily as you can (including cutting down on caffeinated drinks, alcohol and spicy foods) and trying to reduce your stress levels.



The menopause is when a woman stops having periods and is no longer able to get pregnant naturally.

Periods usually start to become less frequent over a few months or years before they stop altogether.
The menopause is a natural part of ageing that usually occurs between 45 and 55 years of age, as a woman’s oestrogen levels decline. In the UK, the average age for a woman to reach the menopause is 51.

Symptoms of the menopause

Most women will experience menopausal symptoms. Some of these can be quite severe and have a significant impact on your everyday activities.

Common symptoms include:

hot flushes
night sweats
vaginal dryness and discomfort during sex
difficulty sleeping
low mood or anxiety
reduced sex drive (libido)
problems with memory and concentration

When to see a GP

It’s worth talking to a GP if you have menopausal symptoms that are troubling you or if you’re experiencing symptoms of the menopause before 45 years of age.

Treatments for menopausal symptoms

Your GP can offer treatments and suggest lifestyle changes if you have severe menopausal symptoms that interfere with your day-to-day life.

These include:

hormone replacement therapy (HRT) – tablets, skin patches, gels and implants that relieve menopausal symptoms by replacing oestrogen
vaginal oestrogen creams, lubricants or moisturisers for vaginal dryness
cognitive behavioural therapy (CBT) – a type of talking therapy that can help with low mood and anxiety
eating a healthy, balanced diet and exercising regularly – maintaining a healthy weight and staying fit and strong can improve some menopausal symptoms
Your GP may refer you to a menopause specialist if your symptoms do not improve after trying treatment or if you’re unable to take HRT.

What causes the menopause?

The menopause is caused by a change in the balance of the body’s sex hormones, which occurs as you get older.

It happens when your ovaries stop producing as much of the hormone oestrogen and no longer release an egg each month.


Most women will experience some symptoms around the menopause. The duration and severity of these symptoms varies from woman to woman.

On average, most symptoms last around 4 years from your last period. However, around 1 in every 10 women experience them for up to 12 years.

Changes to your periods
The first sign of the menopause is usually a change in the normal pattern of your periods. Eventually, you’ll stop having periods altogether.

Common menopausal symptoms

These can have a significant impact on daily life for some women.

Common symptoms include:

hot flushes – short, sudden feelings of heat, usually in the face, neck and chest, which can make your skin red and sweaty
night sweats – hot flushes that occur at night
difficulty sleeping – this may make you feel tired and irritable during the day
a reduced sex drive (libido)
problems with memory and concentration
vaginal dryness and pain, itching or discomfort during sex
mood changes, such as low mood or anxiety
palpitations – heartbeats that suddenly become more noticeable
joint stiffness, aches and pains
reduced muscle mass
recurrent urinary tract infections (UTIs)
The menopause can also increase your risk of developing certain other problems, such as weak bones (osteoporosis).

See your GP if you’re finding your symptoms particularly troublesome, as treatments are available. Read about how to manage symptoms of the menopause.


The main treatment for menopausal symptoms is hormone replacement therapy (HRT), although other treatments are also available for some of the symptoms.

Hormone replacement therapy (HRT)

HRT involves taking oestrogen to replace the decline in your body’s own levels around the time of the menopause. This can relieve many of the associated symptoms.

There are two main types of HRT:

combined HRT (oestrogen and progestogen) – for women with menopausal symptoms who still have their womb (oestrogen taken on its own can otherwise increase your risk of womb cancer)
oestrogen-only HRT – for women who have had their womb removed in a hysterectomy
HRT is available as tablets, skin patches, a gel to rub into the skin or implants.

HRT is extremely effective at relieving menopausal symptoms, especially hot flushes and night sweats, but there are a number of side effects, including breast tenderness, headaches and vaginal bleeding. It’s also associated with an increased risk of blood clots and breast cancer in some women.

HRT is not advisable for some women, such as those who have had certain types of breast cancer or are at high risk of getting breast cancer.

Your GP can give you more information about the risks and benefits of HRT to help you decide whether or not you want to take it.

Hot flushes and night sweats

If you experience hot flushes and night sweats as a result of the menopause, simple measures may sometimes help, such as:

wearing light clothing
keeping your bedroom cool at night
taking a cool shower, using a fan or having a cold drink
trying to reduce your stress levels
avoiding potential triggers, such as spicy food, caffeine, smoking and alcohol
taking regular exercise and losing weight if you’re overweight
If the flushes and sweats are frequent or severe, your GP may suggest taking HRT.

Mood changes

Some women experience mood swings, low mood and anxiety around the time of the menopause.
Self-help measures such as getting plenty of rest, taking regular exercise and doing relaxing activities such as yoga and tai chi may help. Medication and other treatments are also available, including HRT and cognitive behavioural therapy (CBT). Antidepressants may help if you’ve been diagnosed with depression.

Reduced sexual desire

It’s common for women to lose interest in sex around the time of the menopause, but HRT can often help with this.

Vaginal dryness and discomfort

If your vagina becomes dry, painful or itchy as a result of the menopause, your GP can prescribe oestrogen treatment that’s put directly into your vagina as a pessary, cream or vaginal ring.

This can safely be used alongside HRT.

You’ll usually need to use vaginal oestrogen indefinitely, as your symptoms are likely to return when treatment stops. However, side effects are very rare.

You can also use over-the-counter vaginal moisturisers or lubricants in addition to, or instead of, vaginal oestrogen.

Weak bones

Women who have been through the menopause are at an increased risk of developing osteoporosis (weak bones) as a result of the lower level of oestrogen in the body.

You can reduce your chances of developing osteoporosis by:

taking HRT – HRT can help to prevent osteoporosis, although this effect doesn’t tend to last after treatment stops
exercising regularly – including weight-bearing and resistance exercises
eating a healthy diet that includes plenty of fruit, vegetables and sources of calcium, such as low-fat milk and yoghurt
getting some sunlight – sunlight on your skin triggers the production of vitamin D, which can help to keep your bones strong
stopping smoking and cutting down on alcohol
taking calcium and/or vitamin D supplements if you don’t feel you’re getting enough of these – discuss this with your GP

Follow-up appointments

If you’re having treatment for your menopausal symptoms, you’ll need to return to your GP for a follow-up review after 3 months, and once a year after that.

Side Effects

Like all medicines, Livial HRT can cause side effects, although not everyone will experience them. HRT treatments generally cause temporary side effects, but it’s important to speak to your doctor if you have any concerns.

Three of the most common side effects of Livial are:

– Breast pain
– Stomach or pelvic pain
– Unusual hair growth

For a full list of Livial side effects, please see the patient information leaflet.

Because HRT tablets can increase your likelihood of developing a blood clot whilst HRT patches and gels don’t, you should be sure that you have discussed all the risks with your doctor before starting HRT.

The following diseases are more likely to be reported in women taking HRT than those that aren’t:

– Breast cancer
– Endometrial hyperplasia / cancer
– Ovarian cancer
– Blood clots in the veins of the legs or lungs
– Heart disease
– Stroke
– Memory loss (if HRT is started over the age of 65)

Further Information