Azithromycin 500mg Tablets
£23.50 – £37.50
Travellers’ diarrhoea (TD) is a common health problem of overseas travellers to high-risk areas, such as: Asia, Africa, the Middle East and Latin America. These countries are considered high-risk for contracting travellers’ diarrhoea because of poor sanitation and lack of access to clean water. Azithromycin medication is an antibiotic that works by destroying diarrhoea-causing bacteria by stopping them producing their vital proteins. Take one Azithromycin tablet per day at the first sign of an upset stomach (loose stools, nausea or cramps) and the symptoms should clear up within a few days, leaving you fit and well to enjoy your travels.
Travellers’ diarrhoea (TD) is the most common health problem of overseas travellers.
The organisms that cause TD, are reported worldwide, including in the UK. However more commonly affects lower-income countries that have inadequate sanitation facilities and a lack of access to clean water.
There are regional differences in the risk of travellers’ diarrhoea.
Low-risk areas include Western Europe, the United States, Canada, Australia, New Zealand and Japan.
Intermediate-risk areas include southern Europe, Israel, South Africa, some parts of the Caribbean and the Pacific islands.
High-risk areas include most of Asia, the Middle East, Africa, and Latin America.
TD is acquired through the consumption of contaminated food or water.Recreational water such as swimming pools, the sea and freshwater rivers and lakes may also be a source of water-borne infection. In swimming pools, infection may occur if treatment and disinfection of the water are inadequate.
Signs and symptoms
TD is defined as three or more unformed stools in a 24 hour period, often accompanied by at least one of the following: fever, nausea, vomiting, cramps, or bloody stools (dysentery), with symptoms usually starting during or shortly after a period of foreign travel . TD typically occurs during the first week of arrival and is often self-limiting, lasting three to four days.
Diagnosis and treatment
TD is caused by a variety of organisms. Where aetiology is known, bacteria are responsible for most cases.TD usually resolves spontaneously. Individuals with ongoing symptoms depending on the history and clinical presentation may require further tests. The aim of treatment of TD is to avoid dehydration, reduce the severity and duration of symptoms and reduce the interruption to travel plans.
Diet and fluid
Travellers should maintain adequate fluid intake to avoid dehydration. For a mild TD illness oral fluids are often all that is necessary.Adults without existing health problems, with mild to moderate symptoms, can usually stay hydrated by continuing to drink and eat as normal. For more severe symptoms or those prone to complications from dehydration, oral rehydration powders can be diluted into clean drinking water to remedy electrolyte (sugar/salt) imbalances. Consumption of small quantities of easily digestible foods are recommended to aid gut recovery in those with TD.
The most common symptomatic treatments for TD are antimotility agents (e.g. loperamide), and bismuth subsalicylate. Loperamide can be considered for travellers when frequent diarrhoea is inconvenient.
Antibiotic treatment can be considered for treatment of moderate to severe travellers’ diarrhoea.
Travellers should seek medical care if symptoms do not improve within three days. They should seek medical care immediately if they have a fever of 38oC or more, blood and/or mucous in the stool or other worrying symptoms such as altered mental status, severe abdominal pain, jaundice or rash.
Azithromycin is a form of antibiotic that can be used to treat a variety of infections caused by bacteria. Azithromycin can destroy the bacteria which are responsible for causing diarrhoea, by preventing them producing the proteins they need to survive.
It is the recommended treatment for traveller’s diarrhoea, particular for those travelling to South Asia (India, Bangladesh, the Maldives, Sri Lanka, Bhutan, Nepal, Pakistan), or South East Asia (Thailand, Malaysia, Indonesia, Laos, Vietnam, Cambodia, Burma, Philippines)
Azithromycin is highly effective (97% effective) in the treatment of diarrhoea caused by bacteria. Azithromycin can reduce the length of your diarrhoea episode from 3-4 days to 1-2 days. If the diarrhoea persists, consult a doctor
You should start treatment as soon as you notice any of the symptoms of diarrhoea: frequent loose stools, nausea and cramps. The sooner you start treatment, the quicker your recovery will be.
How to take Azithromycin
The Azithromycin tablets can be taken with or without food.
The tablets should be taken with ½ glass of water
Take one 500mg tablet a day for three days, ensuring you complete the course.
You should start taking Azithromycin as soon as you get traveller’s diarrhoea but not before. It is not a preventative treatment. It should not be taken alongside any other traveller’s diarrhoea medication.
Do not take Azithromycin if:
• you are allergic to Azithromycin dihydrate, erythromycin or any macrolide or ketolide antibiotic
• you are allergic to any of the other ingredients of this Azithromycin medicine.
Preventing Travellers’ diarrhoea
TD is difficult to prevent for those who cannot prepare their own food and drinks however the following tips may help.
Travellers should always be prepared to manage the symptoms of TD.
Hands should be washed after visiting the toilet, and always before preparing or eating food. Alcohol gel can be helpful when hand-washing facilities are not available.
Travellers should also practise good swimming pool hygiene by not swimming if they have diarrhoea, ensuring babies and infants are wearing suitable swimwear, and avoiding ingesting any pool water.
Very common (may affect more than 1 in 10 people)
• abdominal pain
• feeling sick (nausea)
• loose wind (flatulence).
Common (may affect up to 1 in 10 people)
• lack of appetite (anorexia)
• feeling dizzy
• sensation of pins and needles or numbness (paraesthesia)
• changes in your sense of taste
• visual impairment
• being sick (vomiting), stomach pain or cramps, loss of appetite,
problems digesting your food
• skin rashes and itching
• joint pain (arthralgia)
• change in the quantity of the white blood cells and the
concentration of bicarbonate in the blood.
For a full list of side effects please see patient information leaflet
Further information can be found on the manufacturers
Paitient Information Leaflet and printed if required.