Pro Plus is available in the following sizes -

• Pro Plus 24 Tablets
• Pro Plus 48 Tablets

Pro Plus contains can help to maintain mental alertness and make you feel less tired.

Each Pro Plus tablet contains: 50 mg of the active ingredient, caffeine, a stimulant that can help to maintain mental alertness and make you feet less tired.

• Pro Plus tablets are for temporary tiredness

How to take Pro Plus Tablets:

Adults and children over 16 years: 1 to 2 tablets with water, if preferred, as required during the day.

• Do not take more than 2 tablets every three hours or 8 tablets in 24 hours
• Not suitable for children under 16
• If you take more than the recommended dose, ask your doctor of pharmacist for advice

You must not take Pro Plus if:

• you are sensitive to caffeine or any of the other ingredients
• you have high blood pressure or are taking other medicines to treat high blood pressure (examples include beta blockers such as atenolol, metoprolol, oxprenolol and propranolol)
• you are taking decongestants containing ephedrine
• you have a history of anxiety or if you have ever had heart rhythm disorder (e.g. rapid or irregular heartbeat)

Caffeine can interfere with how some other medicines work

Do not take Pro Plus if you are taking any of the following medicines -

• antidepressants (e.g. Monoamine oxidase inhibitors or lithium carbonate)
• anxiolytics (also known as tranquillizers)
• antipsychotic medicines such as clozapine
• sedatives such as diazepam
• theopylline (used to treat asthma)
• disulfiram used to treat chronic alcoholism

Do not take Pro Plus if you are pregnant or if you are breast feeding

Pro Plus contains sorbitol and should not be taken by persons with sugar (sucrose) or
fructose intolerance

Before taking Pro Plus tablets consult your doctor or a pharmacist if you taking any of the following medicines:

• phenylpropanolamine (which is found in some cough medicines)
• monoamine oxidase inhibitors such as phenelzine (used for depression)
• methoxsalen (used to treat the skin condition psoriasis)
• phenytoin (used in the treatment of epilepsy)
• pipedemic acid (used occasionally to treat urinary tract infections (bladder infections))
• levothyroxin (used for treatment of thyroid conditions)
• adenosine and dipyridamole (used during hospital tests for heart conditions)

Tiredness is not always caused by a lack of sleep or rest. There may be underlying medical reasons so if tiredness persists consult your doctor.

If you are not used to caffeine or are sensitive to caffeine you may be more likely to experience undesirable effects: If you do not take more than the recommended 400mg of caffeine per day side effects are unlikely but you must remember to take into account the caffeine you are taking in from coffee, tea etc. Some people are more sensitive to caffeine, and can get side effects at lower doses especially if they have never had caffeine before or have not had caffeine for some time. These side effects may include tremor, insomnia, nervousness, irritability, anxiety, headache, tinnitus (ringing in the ears) and stomach complaints (e.g. nausea, vomiting and diarrhoea). You may also notice palpitations, changes in heartbeat, an increased need to pass water and rapid breathing.

Tell your doctor or pharmacist if you experience any other unusual effects after taking Pro Plus

There are some people who may experience effects when they stop taking Pro Plus tablets and/or foods and drinks containing caffeine. The most common effect is headache, but also tiredness and decreased alertness can occur. These effects are temporary, and may last up to a week, but to minimise these effects it is best to gradually reduce caffeine intake.

Caffeine, the active ingredient in Pro Plus, is also found naturally in foods, in particular coffee, tea and chocolate as well as some carbonated drinks. Some medicines (in particular cough cold remedies and pain killers) also contain caffeine. The amount of caffeine in a drink of coffee and tea depends on how they are made. As a guide, filter coffee contains about 50 -100mg of caffeine per 100ml, tea and instant coffee has between 20 and 73mg per 100ml. Chocolate contains between 5 and 20mg of caffeine per 100g, and cola drinks have up to 20mg per 100ml. (100ml is about the same as a small cup/glass).

Each Pro Plus tablet contains 50mg of caffeine and up to 8 tablets (or 400mg of caffeine) may be taken per day. If you also drink coffee, tea and cola drinks, and have had chocolate, reduce the number of Pro Plus tablets you take in a day. If you drink decaffeinated drinks and do not have caffeine from other foods you can take up to 8 Pro Plus tablets a day.